TEAM

Yana K. Reshetnyak PhD, Co-Founder, Director, President and CEO

Yana Reshetnyak is founder, President and CEO of pHLIP, Inc.
Yana leads the clinical translation of pHLIP® imaging products, development of pHLIP® therapeutic products and comprehensive IP portfolio, establishing strategic partnerships with Industry, and negotiation of sublicensing deals.
Yana is an inventor of the pHLIP® technology and expert in fluorescence imaging, membrane biophysics, oncology, drug delivery and therapy. As a Professor at the Physics Department, the University of Rhode Island she has been leading her laboratory in the development of pHLIP® technology and managing multi-million and multi-PI NIH and DoD grants and contracts for more than 15 years. She is a co-author of more than 100 papers and more than 30 patents and patent applications. She was Director Medical Physics program from 2010 to 2019.

Donald M. Engelman PhD, Co-Founder, Director and Chairman of Scientific Board

Donald Engelman is the Eugene Higgins Professor of Molecular Biophysics & Biochemistry at Yale, and a Member of the Yale Cancer Center. He is an elected member of the National Academy of Sciences, the American Academy of Arts and Sciences, and other societies. Don is an inventor of the pHLIP® technology and an expert in membrane biophysics, biochemistry, cell and molecular biology, and cancer biology. Don has many years of experience as a consultant and served as a Director of the Stryker Corporation for more than 20 years. He has led review and steering groups at the NIH, NSF, American Cancer Society, Brookhaven National Laboratory, Los Alamos National Laboratory, and the Institut Laue Langevin, among others. He has also served on a number of nonprofit boards, including the Wenner-Gren foundation and the Board of Trustees of Reed College.

Oleg A. Andreev PhD, Co-Founder, Director, Chairman and Member of Scientific Board

Oleg Andreev is the Professor of Physics at the University of Rhode Island (URI). Oleg has led the Physics Department from 2013 to 2019, and was a member of the URI Intellectual Property Committee for many years. Oleg Andreev is an inventor of the pHLIP® technology and founder of the company. Oleg is an expert in biochemistry, optics, imaging, cancer nanotechnology, and animal studies. He has decade of experience in the development of pHLIP® imaging and therapeutic products. Oleg is an author in more than 100 articles published in scientific journals, and 30 patents and patent applications. Oleg was PI and co-PI in a number of NIH and DoD grants for more than $10 mln in total. Oleg has had industry experience as a Lead Scientist in a Harvard-based Startup.

Jason S. Lewis, PhD, Co-Founder, Member of Scientific Board

Jason Lewis is the Emily Tow Jackson Chair in Oncology at Memorial Sloan Kettering Cancer Center (MSKCC) and currently serves as Vice Chair for Research and as the Chief of the Radiochemistry & Imaging Sciences Service in MSKCC’s Department of Radiology. He is the Director of MSKCC’s Radiochemistry and Molecular Imaging Probe Core Facility and is Director of the MSKCC Center for Molecular Imaging & Nanotechnology. He is a Member in MSKCC, Laboratory Head in the Sloan-Kettering Institute’s Molecular Pharmacology and Chemistry Program, and a Professor at the Gerstner Sloan-Kettering Graduate School of Biomedical Sciences and at Weill-Cornell Medical College. He served as the President of the World Molecular Imaging Society (2014-2015), and was named a Fellow of the World Molecular Imaging Society and was the 2017 SNMMI Michael J. Welch Award winner.

Daniel Greenberg, Director

Daniel Greenberg, a graduate of Reed College and the Univ of Chicago Law School, was chairman and CEO of Electro Rent, (NASDAQ). He Has been a member of Business Executives for National Security and is currently a founding member and former Board Member of the American Business Conference. Previously he served as a Director of Nevada Savings and Loan and the House of Fabrics. He was appointed by the Carnegie Endowment for International Peace to the Mexico United States Consultative group. Dan has served and serves as a Trustee of Care, the NPR Foundation, Trustee of ClientEarth and EarthJustice, Craft and Folk Museum, the Broad Stage in Santa Monica, California and currently chairs the Getty Museum Photography Council. He is a Trustee at Reed College, where he has been a member for over 40 years and Chairman from 2002-2010.

Brian Nath, Director

Brian Nath is Director of Intellectual Property and Commercialization for the University of Rhode Island and Director of Operations for the University of Rhode Island Research Foundation. Brian has been involved with the management and licensing of intellectual property for academic institutions for over ten years.

Douglas Karp, Director

Douglas Karp has more than 20 years of private equity experience leading, managing and exiting investments in growth companies. Prior to founding Pacific Partners LLC, Mr. Karp developed his expertise at Warburg Pincus, Tailwind Capital, Salomon Brothers and the Boston Consulting Group. During his tenure at Warburg, Doug was responsible for $4 billion of communications, media and restructuring investments in the portfolio, and the Warburg funds outperformed the S&P 500 and Russell 2000 by over 1500 basis points. Mr. Karp co-founded Tailwind Capital in 2003, assuming responsibility for the management of the $1.3 billion Thomas Weisel Capital Partners fund and the creation and investment of the Tailwind fund. Doug led Tailwind’s investments in Aircast, Freedom Innovations, SDI Health, Trover and VersaPharm, as well as the development of Tailwind’s growth-oriented investment strategy.

Peter M. Glazer, MD, PhD, Member of Scientific Board

Peter Glazer is the Hunter Professor of Therapeutic Radiology, Genetics and Chair of the Department of Therapeutic Radiology at Yale University. He has had longstanding research interests in tumor hypoxia, DNA repair, cancer therapy and gene editing. He has conducted NIH funded research programs in these areas for over 25 years, recently receiving an Outstanding Investigator Award from the NCI. Dr. Glazer has served as the program leader of the Yale Cancer Center’s Radiobiology and Radiotherapy research program for more than 20 years. Glazer has founded or served on the SAB of several biotech companies, including Codon, Helix, Cybrexa, and Trucode, along with pHLIP. He has received research awards from the American Society for Photobiology, the Radiation Research Society, the Leukemia & Lymphoma Society and the John Yuhas Award from the University of Pennsylvania.

Mark A. Lemmon, PhD, FRS, Member of Scientific Board

Mark Lemmon is the David A. Sackler Professor of Pharmacology at Yale, Co-Director of the Cancer Biology Institute, Associate Director for Basic Science of Yale Cancer Center. Mark’s laboratory focuses on mechanistic, structural, and biochemical aspects of signaling by growth factor receptor tyrosine kinases such as EGF receptor, and on mechanism-guided targeted therapy. Educated in Oxford (BA), Yale (PhD) and NYU (postdoc), he became an Assistant Professor of Biochemistry and Biophysics at the University of Pennsylvania in 1996. After 20 years at Penn, latterly as Chair of Biochemistry and Biophysics, Mark returned to Yale. He serves on advisory boards of several cancer research programs, and on Editorial Boards of Cell, Molecular Cell, Science Signaling, Biochemical Journal and other journals. He was ASBMB Secretary from 2007 to 2013, received Penn’s Stanley Cohen Research Award and the Protein Society’s Dorothy Crowfoot Hodgkin Award, is an elected Fellow of the Royal Society.

Ruslan M. Medzhitov, PhD, Member of Scientific Board

Ruslan Medzhitov is a Sterling Professor at Yale University School of Medicine and an Investigator of the Howard Hughes Medical Institute. His research interests include the biology of inflammation, metabolism, immunology and evolutionary medicine. Ruslan Medzhitov is a member of the National Academy of Sciences and the National Academy of Medicine. He is a member of the European Molecular Biology Organization, a fellow of the American Academy of Microbiology and a foreign member of the Russian Academy of Sciences. His awards include William B. Coley Award, Cancer Research Institute, 2003; Emil von Behring Award, 2004; AAI BD Biosciences Investigator Award, 2006; Blavatnik Award for Young Scientists, 2007; Howard Taylor Ricketts Award, The University of Chicago, 2008; Lewis S. Rosenstiel Award, Brandeis University, 2010; The Shaw Prize in Life Science and Medicine, 2011; Vilcek Prize, New York, 2013; Lurie Prize, Chicago, 2013; Else Kröner Fresenius Stiftung Prize, Germany, 2013 and Charles W. Bohmfalk Teaching Prize, 2015.
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David Wolfsohn, MD, AGAF, FACG, Member of Scientific Board

David Wolfsohn is Assistant Clinical Professor at both the Yale School of Medicine and the Frank H. Netter MD School of Medicine. He is a managing partner at Connecticut Gastroenterology Consultants. David is a Board Certified Gastroenterologist and a Fellow of the American Gastroenterology Association, American College of Gastroenterology, and Jonathan Edwards College of Yale University. He is the recipient of the Vincent A. DeLuca Yale Teaching Award and a member of the Yale GI Leadership Committee. He is the past Governor of Connecticut for the American College of Gastroenterology and member of the ACG National Patient Care Committee. He served as the Director of Endoscopy at the Temple-Yale Center for Endoscopy for more than a decade.

IP Team

pHLIP, Inc. has exclusive rights to a comprehensive and growing Intellectual Property (IP) portfolio, which was built by the team of Dr. Ingrid A. Beattie, a member at Mintz Levin.

 

Legal Team

On corporate financings, collaborative research agreements, licensing agreements with universities, commercial sublicensing agreements with industry partners and other corporate and transactional legal matters, pHLIP is represented by a team of lawyers at our outside counsel Ropes & Gray LLP, led by partners, Steven A. Wilcox and Dr. Melissa Rones.