Atomic structures of pHLIP® peptides

TEAM

Yana K. Reshetnyak PhD, Co-Founder, Director, President and CEO

Yana Reshetnyak is a founder, President and CEO of pHLIP, Inc. She leads the clinical translation of pHLIP® imaging products, development of pHLIP® therapeutic products, establishing strategic partnerships with Industry, and negotiation of sublicensing deals. Yana is an inventor of the pHLIP® technology and an expert in fluorescence imaging, membrane biophysics, oncology, drug delivery and therapy. As a Professor of Biophysics and Medical Physics, in the Physics Department at the University of Rhode Island, and Adjunct Professor of Radiation Oncology at the Brown Medical School, she has been leading her laboratory in the development of pHLIP® technology and managing multi-million and multi-PI grants for more than 15 years. She created a newly Accredited Medical Physics Program at URI in partnership with the Lifespan Hospitals, Brown Medical School.

Donald M. Engelman PhD, Co-Founder, Director and Chairman of Scientific Board

Donald M. Engelman is the Eugene Higgins Professor of Molecular Biophysics and Biochemistry at Yale, and a Member of the Yale Cancer Center. He is an elected member of the National Academy of Sciences, the American Academy of Arts and Sciences, and other societies. Don is an inventor of the pHLIP® technology and an expert in membrane biophysics, biochemistry, cell and molecular biology, and cancer biology. Don has many years of experience as a consultant and served as a Director of the Stryker Corporation for more than 20 years. He has led review and steering groups at the NIH, NSF, American Cancer Society, Brookhaven National Laboratory, Los Alamos National Laboratory, and the Institut Laue Langevin, among others. He has also served on a number of nonprofit boards, including the Wenner-Gren foundation and the Board of Trustees of Reed College.

Oleg A. Andreev PhD, Co-Founder, Director and Chairman

Oleg Andreev is an inventor of the pHLIP® technology and an expert in biochemistry, optics, imaging, cancer nanotechnology, and animal studies. Oleg is Professor and Chair of the Physics Department at the University of Rhode Island, and Adjunct Professor of Radiation Oncology at the Brown Medical School. He has experience in the development of pHLIP® imaging and therapeutic products, and was a member of the URI Intellectual Property Committee for many years. Oleg has more than 70 articles published, 23 patents and patent applications. Oleg has led the Physics Department at URI for the last six years. Under his leadership a new program, Medical Physics, was developed at the Department. Oleg was PI and co-PI in a number of NIH and DoD grants for more than $7 mln in total. Oleg has had industry experience as a Lead Scientist in a Harvard-based Startup.

Jason S. Lewis, PhD, Co-Founder, Member of Scientific Board

Jason Lewis is the Emily Tow Jackson Chair in Oncology at Memorial Sloan Kettering Cancer Center (MSKCC) and currently serves as Vice Chair for Research and as the Chief of the Radiochemistry & Imaging Sciences Service in MSKCC’s Department of Radiology. He is the Director of MSKCC’s Radiochemistry and Molecular Imaging Probe Core Facility and is Director of the MSKCC Center for Molecular Imaging & Nanotechnology. He is a Member in MSKCC, Laboratory Head in the Sloan-Kettering Institute’s Molecular Pharmacology and Chemistry Program, and a Professor at the Gerstner Sloan-Kettering Graduate School of Biomedical Sciences and at Weill-Cornell Medical College. He served as the President of the World Molecular Imaging Society (2014-2015), and was named a Fellow of the World Molecular Imaging Society and was the 2017 SNMMI Michael J. Welch Award winner.

Daniel Greenberg, Director

Daniel Greenberg, a graduate of Reed College and the Univ of Chicago Law School, was chairman and CEO of Electro Rent, (NASDAQ). He Has been a member of Business Executives for National Security and is currently a founding member and former Board Member of the American Business Conference. Previously he served as a Director of Nevada Savings and Loan and the House of Fabrics. He was appointed by the Carnegie Endowment for International Peace to the Mexico United States Consultative group. Dan has served and serves as a Trustee of Care, the NPR Foundation, Trustee of ClientEarth and EarthJustice, Craft and Folk Museum, the Broad Stage in Santa Monica, California and currently chairs the Getty Museum Photography Council. He is a Trustee at Reed College, where he has been a member for over 40 years and Chairman from 2002-2010.

Douglas Karp, Director

Douglas Karp has more than 20 years of private equity experience leading, managing and exiting investments in growth companies. Prior to founding Pacific Partners LLC, Mr. Karp developed his expertise at Warburg Pincus, Tailwind Capital, Salomon Brothers and the Boston Consulting Group. During his tenure at Warburg, Doug was responsible for $4 billion of communications, media and restructuring investments in the portfolio, and the Warburg funds outperformed the S&P 500 and Russell 2000 by over 1500 basis points. Mr. Karp co-founded Tailwind Capital in 2003, assuming responsibility for the management of the $1.3 billion Thomas Weisel Capital Partners fund and the creation and investment of the Tailwind fund. Doug led Tailwind’s investments in Aircast, Freedom Innovations, SDI Health, Trover and VersaPharm, as well as the development of Tailwind’s growth-oriented investment strategy.

David Wolfsohn, MD, AGAF, FACG, Member of Scientific Board

David Wolfsohn is Assistant Clinical Professor at both the Yale School of Medicine and the Frank H. Netter MD School of Medicine. He is a managing partner at Connecticut Gastroenterology Consultants. David is a Board Certified Gastroenterologist and a Fellow of the American Gastroenterology Association, American College of Gastroenterology, and Jonathan Edwards College of Yale University. He is the recipient of the Vincent A. DeLuca Yale Teaching Award and a member of the Yale GI Leadership Committee. He is the past Governor of Connecticut for the American College of Gastroenterology and member of the ACG National Patient Care Committee. He served as the Director of Endoscopy at the Temple-Yale Center for Endoscopy for more than a decade.

Brian Nath, Director

Brian Nath is Director of Intellectual Property and Commercialization for the University of Rhode Island and Director of Operations for the University of Rhode Island Research Foundation. Brian has been involved with the management and licensing of intellectual property for academic institutions for over ten years.

IP Team

pHLIP, Inc. has exclusive rights to a comprehensive and growing Intellectual Property (IP) portfolio, which was built by the team of Dr. Ingrid A. Beattie, a member at Mintz Levin.

 

Legal Team

On corporate financings, collaborative research agreements, licensing agreements with universities, commercial sublicensing agreements with industry partners and other corporate and transactional legal matters, pHLIP is represented by a team of lawyers at our outside counsel Ropes & Gray LLP, led by partners, Steven A. Wilcox and Dr. Melissa Rones.